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The α chain (CD25) is induced during T-cell activation
Initially described as a transcription factor that activates the expression of the cytokine interferon β
a positively charged transmembrane arginine that couples to the ITAM-bearing adaptors CD3ζ and FcεRγ
its cytoplasmic tail recruits the kinase Lck to initiate intracellular signaling cascades crucial for T cell activation and target cell killing
ERCC1 is also required for homology-directed repair (HDR) of DNA double-strand breaks
PPP2R1A Rabbit Polyclonal Antibody Size:100μl The α chain (CD25) isProduct Specification Host Rabbit Antigen PPP2R1A Synonyms Serine threonine protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform; PP2Aa; Medium tumor antigen associated 61 kDa protein; PP2A subunit A isoform PR65 alpha; PP2A subunit A isoform R1 alpha Immunogen Synthetic Peptide Location Nucleus, Cell membrane Accession P30153 Antibody Type Polyclonal antibody Isotype IgG Application WB, IHC P, ICC Reactivity Hu, Ms, Rt, Mk Positive Sample
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